The Ganados are the main enemy in The Armored Werewolf's Let's Play Resident Evil 4. They are villagers, cultists, and soldiers being brainwashed by the Las Plagas parasite.
The villagers are obviously found during the Village segment of Resident Evil 4. Most of them have either a pitchfork, hatchet, or even a knife. One Ganado called Dr. Salvatore wields a chainsaw that instantly kills you.